Here is what I did (but for Norton 2010):

To work around this problem, go to Norton Antivirus 2009 "Computer settings", and click on "Scan exclusions" -> "+Configure". This will open Scan Exclusions dialog. Click Add button in lower (Auto-protect exclusions) part of the dialog and add path to your OrangeCD database files. (Usually the path is ...\My Documents\My Music). Press OK and OK again. This should fix the issue and allow to run OrangeCD with antivirus turned on.