My previous post mistakenly assumed you were using Norton Antivirus which I use at home where I have Orange CD.
My office computer uses Symantec Corporate which I believe is the product that Endpoint Protection derived from. I don't use Orange CD on that machine but I will look at it and see if I can figure out how to setup scan exclusions with it. It may not be the same as Endpoint but I will take a look.
Our corporate machines may also be setup so configuring exclusions may be in the domain of our IT department.